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Patients with early Lebers disease (hereditary optic nerve atrophy) who were treated with vitamin B12 suffered severe and swift optic atrophy

The frequency of B12 injections varies based on individual needs: For deficiency correction: Injections may be administered more frequently, such as weekly or monthly, until levels normalize. For maintenance: Once adequate levels are achieved, monthly injections are typically recommended

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If serum B12 is below 300 pg/mL, further testing is warranted